| 1º Fecha | ||||||
| 06/08/2010 | Kerkrade | Roda | 0 | |||
| Twente | 0 | |||||
| 07/08/2010 | Nijmegen | NEC | 1 | Zomer | ||
| Venlo | 0 | |||||
| 07/08/2010 | Doetinchem | De Graafschap | 3 | Poepon, Nalbantoglu, De Ridder | ||
| Excelsior | 0 | |||||
| 07/08/2010 | Almelo | Heracles | 3 | Vejinovic, Plet (2) | ||
| Willem II | 0 | |||||
| 07/08/2010 | Heerenveen | Heerenveen | 1 | Kopic | ||
| PSV Eindhoven | 3 | Toivonen (2), Engelaar | ||||
| 08/08/2010 | Groningen | Groningen | 2 | Matavz, Pedersen | ||
| Ajax | 2 | El Hamdaoui (2) | ||||
| 08/08/2010 | Rotterdam | Feyenoord | 3 | Schut (A), Bruins, Fer | ||
| Utrecht | 1 | Van Wolfswinkel | ||||
| 08/08/2010 | Arnhem | Vitesse | 3 | Pluim, Nilsson (2P) | ||
| Ado den Haag | 1 | Immers | ||||
| 08/08/2010 | Breda | NAC | 1 | Amoah | ||
| AZ | 1 | Falkenburg | ||||
| 2º Fecha | ||||||
| 14/08/2010 | Amsterdam | Ajax | 4 | Vertonghen, Van der Wielo, De Jong, Anita | ||
| Vitesse | 2 | Propper, Van Ginkel | ||||
| 14/08/2010 | Alkmaar | AZ | 1 | Martens | ||
| Groningen | 1 | Spary | ||||
| 14/08/2010 | Eindhoven | PSV Eindhoven | 6 | Dzsudzzsak (P), Toivonen (3), Amrabat, Afellay | ||
| De Graafschap | 0 | |||||
| 14/08/2010 | Venlo | Venlo | 1 | Boymans | ||
| Heracles | 0 | |||||
| 14/08/2010 | Enschede | Twente | 0 | |||
| Heerenveen | 0 | |||||
| 15/08/2010 | Rotterdam | Excelsior | 3 | Fernandez (2), Bovenberg | ||
| Feyenoord | 2 | Vlaar, Miquel (A) | ||||
| 15/08/2010 | La Haya | Ado den Haag | 1 | Kubik | ||
| Roda | 3 | Junker (P), Delorge, Hempte | ||||
| 15/08/2010 | Utrecht | Utrecht | 3 | Van Wolfswinkel (2, 1P), Mertens | ||
| NAC | 1 | Amoah | ||||
| 15/08/2010 | Tilburg | Willem II | 3 | Hakola, Demouge, Lasnik (P) | ||
| NEC | 5 | Schone, Vleminckx (3, 1P), Sibum | ||||
| 3º Fecha | ||||||
| 20/08/2010 | Rotterdam | Excelsior | 4 | Clasie, Bovenberg, Bergkamp, Fernandez | ||
| NEC | 2 | Vleminckx, Sibum | ||||
| 21/08/2010 | Arnhem | Vitesse | 0 | |||
| Twente | 3 | Janko, De Jong (2) | ||||
| 21/08/2010 | Groningen | Groningen | 2 | Granqvist (P), Enevoldsen | ||
| De Graafschap | 1 | Poepon | ||||
| 21/08/2010 | Heerenveen | Heerenveen | 3 | Dost (2), Luijckx (A) | ||
| NAC | 1 | Amoah | ||||
| 21/08/2010 | Amsterdam | Ajax | 3 | El Hamdaoui (2), Suarez | ||
| Roda | 0 | |||||
| 22/08/2010 | Utrecht | Utrecht | 3 | Van Wolfswinkel (2, 1P), Mertens | ||
| Willem II | 0 | |||||
| 22/08/2010 | Almelo | Heracles | 1 | Looms | ||
| Feyenoord | 1 | Wijnaldum | ||||
| 22/08/2010 | Venlo | Venlo | 2 | Ahahaoui, Boymans | ||
| Ado den Haag | 3 | Bulykin (2), Verhoek | ||||
| 22/08/2010 | Eindhoven | PSV Eindhoven | 3 | Berg (2), Afellay | ||
| AZ | 1 | Falkenburg | ||||
| 4º Fecha | ||||||
| 27/08/2010 | Tilburg | Willem II | 0 | |||
| Groningen | 3 | Hiariej, Enevoldsen, Pedersen | ||||
| 28/08/2010 | Breda | NAC | 2 | Amoah, Gorter | ||
| Venlo | 0 | |||||
| 28/08/2010 | Kerkrade | Roda | 4 | Skoubo (2), Delorge, Junker | ||
| Heracles | 2 | Vejinovic, Overtoom | ||||
| 28/08/2010 | Nijmegen | NEC | 2 | George, Schone | ||
| Heerenveen | 2 | Grindheim, Beerens | ||||
| 29/08/2010 | Doetinchem | De Graafschap | 0 | |||
| Ajax | 5 | Suarez (3), Emanuelson, Eriksen | ||||
| 29/08/2010 | La Haya | Ado den Haag | 2 | Derijck, Kubik | ||
| PSV Eindhoven | 2 | Afellay, Rodriguez | ||||
| 29/08/2010 | Rotterdam | Feyenoord | 4 | Leerdam, Fer, Castaignos, Wijnaldum (P) | ||
| Vitesse | 0 | |||||
| 29/08/2010 | Enschede | Twente | 4 | Janko (2), De Jong (2) | ||
| Utrecht | 0 | |||||
| 29/08/2010 | Alkmaar | AZ | 1 | Sigthorsson | ||
| Excelsior | 1 | Fernandez | ||||
| 5º Fecha | ||||||
| 11/09/2010 | Amsterdam | Ajax | 2 | Suarez (2P) | ||
| Willem II | 0 | |||||
| 11/09/2010 | Venlo | Venlo | 1 | Paauwe (P) | ||
| Twente | 2 | Ruiz, Rosales | ||||
| 11/09/2010 | Heerenveen | Heerenveen | 2 | Beerens (P), Assaidi | ||
| Vitesse | 1 | Propper | ||||
| 11/09/2010 | Eindhoven | PSV Eindhoven | 3 | Koevermans, Afellay, Toivonen | ||
| NEC | 1 | Goossens | ||||
| 11/09/2010 | Alkmaar | AZ | 1 | Elm | ||
| Roda | 2 | Delorge, Janssen | ||||
| 11/09/2010 | Rotterdam | Excelsior | 2 | Bergkamp, Van Steensel | ||
| Heracles | 1 | Fledderus | ||||
| 12/09/2010 | Breda | NAC | 2 | Schilder (2) | ||
| Feyenoord | 0 | |||||
| 12/09/2010 | La Haya | Ado den Haag | 2 | Bulykin, Visser | ||
| De Graafschap | 2 | Bargas (2) | ||||
| 12/09/2010 | Groningen | Groningen | 1 | Granqvist (P) | ||
| Utrecht | 0 | |||||
| 6º Fecha | ||||||
| 17/09/2010 | Doetincham | De Graafschap | 3 | Nalbantoglu, Poepon (2) | ||
| Heerenveen | 2 | Grindheim, Assaidi | ||||
| 18/09/2010 | Groningen | Groningen | 2 | Pedersen, Matavz | ||
| Excelsior | 0 | |||||
| 18/09/2010 | Arnhem | Vitesse | 0 | |||
| NAC | 0 | |||||
| 18/09/2010 | Tilburg | Willem II | 2 | Rigters, Levchenko | ||
| Ado den Haag | 4 | Radosavljevic, Kubik (2) | ||||
| 19/09/2010 | Rotterdam | Feyenoord | 1 | Bahia | ||
| Ajax | 2 | De Jong, El Hamdaoui | ||||
| 19/09/2010 | Utrecht | Utrecht | 3 | Van Wolfswinkel (2, 1P), Asare | ||
| Venlo | 2 | Boymans (2) | ||||
| 19/09/2010 | Nijmegen | NEC | 0 | |||
| AZ | 1 | Jonathas | ||||
| 19/09/2010 | Kerkrade | Roda | 0 | |||
| PSV | 0 | |||||
| 19/09/2010 | Almelo | Heracles | 0 | |||
| Twente | 0 | |||||
| 7º Fecha | ||||||
| 25/09/2010 | Heerenveen | Heerenveen | 2 | Dost (2) | ||
| Roda | 2 | Djum, Junker | ||||
| 25/09/2010 | La Haya | Ado den Haag | 3 | Immers, Bulykin (2) | ||
| Heracles | 2 | Plet, Everton | ||||
| 25/09/2010 | Alkmaar | AZ | 1 | Elm | ||
| Utrecht | 0 | |||||
| 25/09/2010 | Eindhoven | PSV | 1 | Toivonen | ||
| Groningen | 1 | Garcia-Garcia | ||||
| 25/09/2010 | Enschede | Twente | 2 | Janssen (2) | ||
| Ajax | 2 | El Hamdaoui, Enoh | ||||
| 26/09/2010 | Rotterdam | Excelsior | 0 | |||
| Vitesse | 2 | Stevanovic, Aissati | ||||
| 26/09/2010 | Breda | NAC | 2 | Luijckx, Kolkka | ||
| Willem II | 1 | Landgren | ||||
| 26/09/2010 | Nijmegen | NEC | 3 | Schone, Voorde, Nuytinck | ||
| Feyenoord | 0 | |||||
| 26/09/2010 | Venlo | Venlo | 1 | Boymans | ||
| De Graafschap | 0 | |||||
| 8º Fecha | ||||||
| 01/10/2010 | Arnhem | Vitesse | 0 | |||
| Willem II | 0 | |||||
| 02/10/2010 | Breda | NAC | 2 | Amoah, Idabdelhay | ||
| NEC | 0 | |||||
| 02/10/2010 | Rotterdam | Excelsior | 1 | Gudde | ||
| Roda | 2 | Kah, Hadouir | ||||
| 03/10/2010 | Amsterdam | Ajax | 1 | De Jong | ||
| Utrecht | 2 | Van Wolfswinkel (2P) | ||||
| 03/10/2010 | Alkmaar | AZ | 2 | Sighorsson, Jonathas | ||
| Heracles | 1 | Overtoom | ||||
| 03/10/2010 | Doetinchem | De Graafschap | 1 | Bargas | ||
| Feyenoord | 1 | Bruins (P) | ||||
| 03/10/2010 | Heerenveen | Heerenveen | 0 | |||
| Ado den Hag | 0 | |||||
| 03/10/2010 | Enschede | Twente | 4 | Ruiz (2, 1P), Janko, Janssen | ||
| Groningen | 2 | Granqvist (P), Matavz | ||||
| 03/10/2010 | Eindhoven | PSV | 3 | Reis (2), Bouma | ||
| Venlo | 0 | |||||
| 9º Fecha | ||||||
| 16/10/2010 | Amsterdam | Ajax | 3 | Vertoghen, El Hamdaoui, Suarez | ||
| NAC | 0 | |||||
| 16/10/2010 | La Haya | Ado den Hag | 2 | Kubik, Bulykin | ||
| Excelsior | 1 | Vincken (P) | ||||
| 16/10/2010 | Utrecht | Utrecht | 2 | Wuytens, Mulenga | ||
| De Graafschap | 2 | Bargas, De Ridder | ||||
| 16/10/2010 | Venlo | Venlo | 0 | |||
| AZ | 1 | Pelle | ||||
| 16/10/2010 | Rotterdam | Feyenoord | 0 | |||
| Twente | 1 | Landzaat | ||||
| 17/10/2010 | Groningen | Groningen | 1 | Granqvist | ||
| Heerenveen | 0 | |||||
| 17/10/2010 | Kerkrade | Roda | 4 | Djum, Junker (2), Janssen | ||
| Vitesse | 1 | Jenner | ||||
| 17/10/2010 | Tilburg | Willem II | 2 | Landgren, Bouma (A) | ||
| PSV | 4 | Dzsudzsak, Lens, Afellay, Reis | ||||
| 17/10/2010 | Almelo | Heracles | 3 | Overtoom (P), Everton, Amenteros | ||
| NEC | 2 | Davids, Schone (P) | ||||
| 10º Fecha | ||||||
| 22/10/2010 | Breda | NAC | 1 | Kolkka | ||
| Kerkrade | 2 | Djum, Hempte | ||||
| 23/10/2010 | Doetinchem | De Graafschap | 2 | Hersi | ||
| Heracles | 1 | Plet | ||||
| 23/10/2010 | Nijmegen | NEC | 3 | Vleminckx (3) | ||
| Groningen | 2 | Enevoldsen, Anderson | ||||
| 23/10/2010 | Heerenveen | Heerenveen | 2 | Dost, Vayrynen | ||
| Venlo | 0 | |||||
| 24/10/2010 | Rotterdam | Excelsior | 2 | Bovenberg, Wattamaleo | ||
| Ajax | 2 | El Hamdaoui, Vertoghen | ||||
| 24/10/2010 | Alkmaar | AZ | 3 | Jonathas (P), Martens, Holman | ||
| Willem II | 0 | |||||
| 24/10/2010 | Eindhoven | PSV | 10 | Reis (3), Afellay, Toivonen, Lens (2), Dzsudzsak (2,1 P), Engelaar | ||
| Feyenoord | 0 | |||||
| 24/10/2010 | Enschede | Twente | 3 | Janssen, Ruiz (P), Janko | ||
| Ado den Haag | 2 | Bulykin, Kubik | ||||
| 24/10/2010 | Arnhem | Vitesse | 1 | Pedersen | ||
| Utrecht | 4 | Rajkovic (A), Mertens, Cornelisse, Mulenga | ||||
| 11º Fecha | ||||||
| 26/10/2010 | Kerkrade | Roda | 1 | Djum, Hempte | ||
| NEC | 1 | Vleminckx | ||||
| 26/10/2010 | Almelo | Heracles | 4 | Armenteros, Fledderus, Overtoom (P), Plet | ||
| NAC | 1 | Luijckx | ||||
| 27/10/2010 | Amsterdam | Ajax | 3 | El Hamdaoui (2), Anita | ||
| Heerenveen | 1 | Dost | ||||
| 27/10/2010 | Doetinchem | De Graafschap | 2 | Poepon, Bargas | ||
| AZ | 1 | Pelle | ||||
| 27/10/2010 | Groningen | Groningen | 3 | Ivens, Gramqvist, Van de Laak | ||
| Ado den Haag | 1 | Immers | ||||
| 27/10/2010 | Tilburg | Willem II | 1 | Van Zaanen | ||
| Twente | 3 | De Jong (2), Franco | ||||
| 27/10/2010 | Utrecht | Utrecht | 2 | Mulenga, Van Wolfswinkel | ||
| Excelsior | 0 | |||||
| 27/10/2010 | Rotterdam | Feyenoord | 3 | Wijnaldum (2), Bahia | ||
| Venlo | 0 | |||||
| 27/10/2010 | Arnhem | Vitesse | 0 | |||
| PSV | 2 | Reis, Dzudzsak (P) | ||||
| 12º Fecha | ||||||
| 30/10/2010 | Venlo | Venlo | 3 | Toth, Ahahaoui (P), Uchebo | ||
| Groningen | 5 | Matavz (2), Garcia-Garcia, De Regt (A), Van de Laak | ||||
| 30/10/2010 | Rotterdam | Excelsior | 0 | |||
| Heerenveen | 2 | Dost, Assaidi | ||||
| 30/10/2010 | Breda | NAC | 2 | Penders, Gorter (P) | ||
| De Graafschap | 0 | |||||
| 30/10/2010 | Almelo | Heracles | 1 | Overtoom | ||
| Ajax | 4 | El Hamdaoui, Lindgren, Ooijer, Sulejmani | ||||
| 30/10/2010 | Eindhoven | PSV | 0 | |||
| Twente | 1 | Chadli | ||||
| 31/10/2010 | La Haya | Ado deen Haag | 1 | Immers | ||
| Utrecht | 0 | |||||
| 31/10/2010 | Nijmegen | NEC | 0 | |||
| Vitesse | 0 | |||||
| 31/10/2010 | Alkmaar | AZ | 2 | Holman, Pelle | ||
| Feyenoord | 1 | Castaignos | ||||
| 31/10/2010 | Kerkrade | Roda | 2 | Janssen (2) | ||
| Willem II | 2 | Lasnik, Sheotahul | ||||
| 13º Fecha | ||||||
| 05/11/2010 | Tilburg | Willem II | 1 | Rigters | ||
| Venlo | 4 | Boymans (2, 1P), Toth, Viana | ||||
| 06/11/2010 | Enschede | Twente | 2 | Chadli, Janko | ||
| Excelsior | 1 | Van Steensel | ||||
| 06/11/2010 | Groningen | Groningen | 2 | Granqvist (2P) | ||
| NAC | 1 | Granqvist (A) | ||||
| 06/11/2010 | Heerenveen | Heerenveen | 3 | Breuer, Beerens (P), Maertens (A) | ||
| Heracles | 2 | Overtoom (P), Everton | ||||
| 06/11/2010 | Doetinchem | De Graafschap | 1 | Nalbantoglu | ||
| NEC | 4 | Will, Vleminckx (3) | ||||
| 07/11/2010 | Amsterdam | Ajax | 0 | |||
| Ado den Haag | 1 | Verhoek | ||||
| 07/11/2010 | Utrecht | Utrecht | 1 | Demouge | ||
| PSV | 2 | Dzsudzsak (2, 1P) | ||||
| 07/11/2010 | Rotterdam | Feyenoord | 1 | Castaignos | ||
| Roda | 1 | Junker | ||||
| 07/11/2010 | Arnhem | Vitesse | 1 | Aissati | ||
| AZ | 1 | Pelle | ||||
| 14º Fecha | ||||||
| 12/11/2010 | Tilburg | Willem II | 0 | |||
| (*) | De Graafschap | 1 | Overgoor | |||
| 13/11/2010 | Eindhoven | PSV | 4 | Lens, Bouma, Toivonen, Marcelo | ||
| Excelsior | 2 | Bovenberg, Fernandez | ||||
| 13/11/2010 | Breda | NAC | 2 | Boussaboun, Amoah | ||
| Twente | 1 | Ruiz | ||||
| 14/11/2010 | Alkmaar | AZ | 2 | Wernbloom, Sigthorsson | ||
| Ajax | 0 | |||||
| 14/11/2010 | Nijmegen | NEC | 1 | Zomer | ||
| Ado den Haag | 1 | Will (A) | ||||
| 14/11/2010 | Venlo | Venlo | 1 | Boymans (P) | ||
| Vitesse | 5 | Pluim, Jenner, Pedersen (2), Aissati | ||||
| 14/11/2010 | Rotterdam | Feyenoord | 2 | Castaignos, Cabral | ||
| Heerenveen | 2 | Vayrynen, Elm | ||||
| 14/11/2010 | Almelo | Heracles | 3 | Armenteros, Everton, Looms | ||
| Groningen | 0 | |||||
| 25/11/2010 | Kerkrade | Roda | 1 | Vormer | ||
| Utrecht | 1 | Duplan | ||||
| (*) Terminado de jugar el 25/11/10 | ||||||
| 15º Fecha | ||||||
| 20/11/2010 | Rotterdam | Excelsior | 1 | Bergkamp | ||
| Venlo | 0 | |||||
| 20/11/2010 | Arnhem | Vitesse | 2 | Propper, Stevanovic | ||
| Heracles | 0 | |||||
| 20/11/2010 | Enschede | Twente | 1 | De Jong | ||
| AZ | 2 | Elm, Ortiz | ||||
| 20/11/2010 | Doetinchem | De Graafschap | 3 | Poepon (3) | ||
| Roda | 1 | Huysegems | ||||
| 20/11/2010 | Amsterdam | Ajax | 0 | |||
| PSV | 0 | |||||
| 21/11/2010 | Groningen | Groningen | 2 | Matavz (2) | ||
| Feyenoord | 0 | |||||
| 21/11/2010 | Heerenveen | Heerenveen | 5 | Vayrynen, Breuer (2), Beerens (2, 1P) | ||
| Willem II | 0 | |||||
| 21/11/2010 | La Haya | Ado den Haag | 3 | Bulykin, Verhoek, Radosavljevic | ||
| NAC | 0 | |||||
| 21/11/2010 | Utrecht | Utrecht | 4 | Van Wolfswinkel (P), Duplan, Nesu, Demouge | ||
| NEC | 0 | |||||
| 16º Fecha | ||||||
| 26/11/2010 | Breda | NAC | 4 | Leonardo, Amcah, Boussaboun, Amoah | ||
| PSV | 2 | Reis, Dzsudzsak | ||||
| 27/11/2010 | Alkmaar | AZ | 2 | Wernbloom, Sogthorsson | ||
| Heerenveen | 2 | Vayrynen, Janmaat | ||||
| 27/11/2010 | Kerkrade | Roda | 1 | Djoum | ||
| Groningen | 0 | |||||
| 27/11/2010 | Tillburg | Willem II | 1 | Levchenko | ||
| Excelsior | 1 | Ramsleijn | ||||
| 27/11/2010 | Nijmegen | NEC | 2 | Sibum, Vleminckx | ||
| Twente | 4 | Ruiz (2, 1P), Janko (2) | ||||
| 28/11/2010 | Doetinchem | De Graafschap | 1 | Hersi | ||
| Vitesse | 1 | Pluim | ||||
| 28/11/2010 | Rotterdam | Feyenoord | 2 | Radosavljevic (A), Castaignos | ||
| Ado den Haag | 1 | Bulykin, Verhoek, Radosavljevic | ||||
| 28/11/2010 | Almelo | Heracles | 2 | Schut (A), Overtoom (P) | ||
| Utrecht | 1 | Cornelisse | ||||
| 28/11/2010 | Venlo | Venlo | 0 | |||
| Ajax | 2 | Mido, Sulejmani | ||||
| 17º Fecha | ||||||
| 03/12/2010 | Groningen | Groningen | 4 | Granqvist (P), Matavz, Andersson, Spary | ||
| Vitesse | 1 | Pedersen | ||||
| 04/12/2010 | Amsterdam | Ajax | 1 | Mido | ||
| NEC | 1 | Nuytinck | ||||
| 04/12/2010 | Eindhoven | PSV | 5 | Dzsudzsak, Toivonen (2), Afellay, Berg | ||
| Heracles | 2 | Everton (2) | ||||
| 04/12/2010 | Enschede | Twente | 2 | Janssen (2) | ||
| De Graafschap | 0 | |||||
| 05/12/2010 | Tillburg | Willem II | 1 | Van Haaren (A) | ||
| Feyenoord | 1 | Leerdam | ||||
| 05/12/2010 | La Haya | Ado den Haag | 0 | |||
| AZ | 2 | Elm (P), Martens | ||||
| 05/12/2010 | Utrecht | Utrecht | 2 | Mertens, Wuytens | ||
| Heerenveen | 1 | Beerens (P) | ||||
| 14/12/2010 | Venlo | Venlo | 0 | |||
| Roda | 4 | Janssen, Delorge, Junker (2) | ||||
| 15/12/2010 | Rotterdam | Excelsior | 1 | Vincken | ||
| NAC | 3 | Amoah, Schilder, Boussaboun | ||||
| 18º Fecha | ||||||
| 10/12/2010 | Almelo | Heracles | 2 | Everton, Armenteros | ||
| Venlo | 2 | Boymans, Uchebo | ||||
| 11/12/2010 | Breda | NAC | 3 | Feher, Schut (A), Luijckx | ||
| Utrecht | 1 | Siberbauer | ||||
| 11/12/2010 | Nijmegen | NEC | 3 | Verminckx, Schone, Goossens | ||
| Willem II | 1 | Lasnik (P) | ||||
| 11/12/2010 | Kerkrade | Roda | 1 | Janssen | ||
| Ado den Haag | 1 | Bulykin | ||||
| 11/12/2010 | Doetinchem | De Graafschap | 0 | |||
| PSV | 0 | |||||
| 12/12/2010 | Arnehm | Vitesse | 0 | |||
| Ajax | 1 | Eriksen | ||||
| 12/12/2010 | Heerenveen | Heerenveen | 6 | Assaidi (3), Elm, Narsingh, Vayrynen (P) | ||
| Twente | 2 | Chadli (2) | ||||
| 12/12/2010 | Rotterdam | Feyenoord | 1 | Castaignos | ||
| Excelsior | 0 | |||||
| 12/12/2010 | Groningen | Groningen | 2 | Matavz (2) | ||
| AZ | 0 | |||||
| 19º Fecha | ||||||
| 18/12/2010 | Heerenveen | Heerenveen | 4 | Elm, Djuricic, Narsingh (2) | ||
| De Graafschap | 0 | |||||
| 18/12/2010 | Breda | NAC | 1 | Gudelj | ||
| Vitesse | 1 | Jenner | ||||
| 18/12/2010 | Rotterdam | Excelsior | 2 | Koolwijk (P), Bovenberg | ||
| Groningen | 2 | Tadic, Paauwee (A) | ||||
| 18/12/2010 | La Haya | Ado den Haag | 2 | Vossebelt (A), Lampi (A) | ||
| Willem II | 1 | Biemans | ||||
| 19/12/2010 | Eindhoven | PSV | 3 | Lens, Berg, Dzsudzsak | ||
| Roda | 1 | Hadouir | ||||
| 19/01/2011 | Alkmaar | AZ | 2 | Schaars, Falkenburg | ||
| NEC | 2 | Vleminckx (2) | ||||
| 19/01/2011 | Enschede | Twente | 5 | Janko (4), De Jong | ||
| Heracles | 0 | |||||
| 19/01/2011 | Venlo | Venlo | 1 | Leemans | ||
| Utrecht | 2 | Demouge, Yildirim | ||||
| 19/01/2011 | Amsterdam | Ajax | 2 | Alderweireld, Sulejmani (P) | ||
| Feyenoord | 0 | |||||
| 20º Fecha | ||||||
| 21/01/2011 | La Haya | Ado den Haag | 3 | Buijs, Vicento, Immers | ||
| Heerenveen | 1 | Dost | ||||
| 22/01/2011 | Almelo | Heracles | 0 | |||
| AZ | 0 | |||||
| 22/01/2011 | Nijmegen | NEC | 2 | Vleminckx, Goossens | ||
| NAC | 2 | Gudelj, Van der Pluim | ||||
| 22/01/2011 | Tillburg | Willem II | 1 | Janga | ||
| Vitesse | 0 | |||||
| 22/01/2011 | Rotterdam | Feyenoord | 0 | |||
| De Graafschap | 1 | Broekhof | ||||
| 23/01/2011 | Utrecht | Utrecht | 3 | Duplan (2), Vorstermans | ||
| Ajax | 0 | |||||
| 23/01/2011 | Kerkrade | Roda | 3 | Hemple, Modou Kah, Skoubo | ||
| Excelsior | 0 | |||||
| 23/01/2011 | Venlo | Venlo | 0 | |||
| PSV | 3 | Bouma, Lens, Hutchinson | ||||
| 23/01/2011 | Groningen | Groningen | 1 | Matavz | ||
| Twente | 2 | Janko (2) | ||||
| 21º Fecha | ||||||
| 28/01/2011 | Nijmegen | NEC | 1 | Vleminckx | ||
| Heracles | 1 | Fiedderus | ||||
| 29/01/2011 | Vitesse | Vitesse | 5 | Matic, Van Ginkel (2), Lopez (P), Babangida | ||
| Roda | 2 | Junker, Hempte | ||||
| 29/01/2011 | Alkmaar | AQZ | 6 | Sigthorsson (5), Gudmundsson | ||
| Venlo | 1 | Musa | ||||
| 29/01/2011 | Eindhoven | PSV | 2 | Toivonen, Zeeluk | ||
| Willem II | 1 | Biemans | ||||
| 30/01/2011 | Rotterdam | Excelsior | 1 | Vincken | ||
| Ado den Haag | 5 | Bulykin (2), Kubik, Toornstra, Verhoek | ||||
| 30/01/2011 | Enschede | Twente | 2 | Brama, Ruiz | ||
| Feyenoord | 1 | Swerts | ||||
| 30/01/2011 | Heerenveen | Heerenveen | 1 | Djuricic | ||
| Groningen | 4 | Ivens, Matavz, Tadic (2) | ||||
| 30/01/2011 | Breda | NAC | 0 | |||
| Ajax | 3 | De Jong, Penders (A), Sulejmani | ||||
| 01/02/2011 | Doetinchem | De Graafschap | 0 | |||
| Utrecht | 0 | |||||
| 22º Fecha | ||||||
| 04/02/2011 | Amsterdam | Ajax | 2 | El Hamdaoui, De Jong | ||
| De Graafschap | 0 | |||||
| 05/02/2011 | Heerenveen | Heerenveen | 0 | |||
| NEC | 0 | |||||
| 05/02/2011 | Rotterdam | Excelsior | 2 | Vincken (P), Clasie | ||
| AZ | 1 | Sigthorsson | ||||
| 05/02/2011 | Eindhoven | PSV | 0 | |||
| Ado den Haag | 1 | Verhoek | ||||
| 05/02/2011 | Venlo | Venlo | 3 | Musa, Chula, Ahahaoui | ||
| NAC | 0 | |||||
| 06/02/2011 | Arnhem | Vitesse | 1 | Assati (P) | ||
| Feyenoord | 1 | Castaignos | ||||
| 06/02/2011 | Utrecht | Utrecht | 1 | De Kogel | ||
| Twente | 1 | Chadhi | ||||
| 06/02/2011 | Groningen | Groningen | 7 | Granqvist, Stenman, Matavz, Enevoldsen, Tadic | ||
| Willem II | 1 | Lasnik (P) | ||||
| 06/02/2011 | Almelo | Heracles | 1 | Overtoom | ||
| Roda | 0 | |||||
| 23º Fecha | ||||||
| 12/02/2011 | La Haya | Ado den Haag | 3 | Toomstra, Bulyan (2, 1P) | ||
| Venlo | 0 | |||||
| 12/02/2011 | Tillburg | Willem II | 3 | Van der Heijden, Hakola, Rigters | ||
| Utrecht | 3 | Mertens (2), Vorstermans | ||||
| 12/02/2011 | Enschede | Twente | 1 | Chadi | ||
| Vitesse | 0 | |||||
| 12/02/2011 | Rotterdam | Feyenoord | 2 | Miyaishi, Biseswar | ||
| Heracles | 1 | Fledderus | ||||
| 12/02/2011 | Alkmaar | AZ | 0 | |||
| PSV | 4 | Berg (2), Dzsudzsak (2) | ||||
| 13/02/2011 | Breda | NAC | 0 | |||
| Heerenveen | 2 | Narsingh, Assaid | ||||
| 13/02/2011 | Kerkrade | Roda | 2 | Junker, Hadouir | ||
| Ajax | 2 | Sulejmani, De Jong | ||||
| 13/02/2011 | Nijmegen | NEX | 2 | Zimling (2) | ||
| Excelsior | 0 | |||||
| 13/02/2011 | Doetinchem | De Graafschap | 1 | Poepon | ||
| Groningen | 1 | Holla | ||||
| 24º Fecha | ||||||
| 18/02/2011 | Utrecht | Utrecht | 1 | Van Wolfswinkel | ||
| Heracles | 1 | Cairo | ||||
| 19/02/2011 | Rotterdam | Excelsior | 4 | Roorda (2, 1P), Lagoulreh, Fernandez | ||
| Willem II | 0 | |||||
| 19/02/2011 | Heerenveen | Heerenveen | 0 | |||
| AZ | 2 | Wernbloom, Moreno | ||||
| 19/02/2011 | Groningen | Groningen | 1 | Pedersen | ||
| Roda | 4 | Junker (3), Bodor | ||||
| 20/02/2011 | La Haya | Ado den Haag | 2 | Vicento, Bulykin | ||
| Feyenoord | 2 | Castaignos (2) | ||||
| 20/02/2011 | Amsterdam | Ajax | 1 | El Hamdaoui | ||
| Venlo | 0 | |||||
| 20/02/2011 | Arnhem | Vitese | 2 | Bony, Matic | ||
| De Graafschap | 0 | |||||
| 20/02/2011 | Enschede | Twente | 1 | Bajrami | ||
| NEC | 1 | Zimling | ||||
| 20/02/2001 | Eindhoven | PSV | 4 | Dzsudzsak, Lens, Toivonen, Rodriguez | ||
| NAC | 1 | Lurling | ||||
| 25º Fecha | ||||||
| 25/02/2011 | Venlo | Venlo | 1 | Cullen | ||
| Excelsior | 0 | |||||
| 26/02/2011 | Tillburg | Willem II | 4 | Biemans, Swinkels, Van der Hejden, Rigters | ||
| Heerenveen | 3 | Janmaat, Dost, Vayrynen | ||||
| 26/02/2011 | Kerkrade | Roda | 1 | Skoubo | ||
| De Graafschap | 1 | De Ridder | ||||
| 26/02/2011 | Almelo | Heracles | 6 | Looms, Everton, Fledderus, Overtoom (2), Kashia (A) | ||
| Vitesse | 1 | Kashia | ||||
| 26/02/2011 | Breda | NAC | 3 | Schilder (2), Feher | ||
| Ado den Haag | 2 | Verhoek, Horvath (A) | ||||
| 27/02/2011 | Rotterdam | Feyenoord | 5 | Wijnaldum (4, 2P), Vlaar | ||
| Groningen | 1 | Pedersen | ||||
| 27/02/2011 | Eindhoven | PSV | 0 | |||
| Ajax | 0 | |||||
| 27/02/2011 | Alkmaar | AZ | 2 | Janssen (A), Falkenburg | ||
| Twente | 1 | De Jong | ||||
| 27/02/2011 | Nijmegen | NEC | 1 | Goossens | ||
| Utrecht | 1 | Van Wolfswinkel | ||||
| 26º Fecha | ||||||
| 04/03/2011 | Doetinchem | De Graafschap | 2 | Poepon, Bargas | ||
| Willem II | 1 | Hakola | ||||
| 05/03/2011 | Enschede | Twente | 2 | De Jong, Chadli | ||
| NAC | 0 | |||||
| 05/03/2011 | La Haya | Ado den Haag | 5 | Immens, Bulykin (P); Verhoek, Toonstra, Brouwer | ||
| NEC | 1 | Vleminckx | ||||
| 05/03/2011 | Arnhem | Vitesse | 2 | Van Ginkel, De Regt (A) | ||
| Venlo | 0 | |||||
| 05/03/2011 | Rotterdam | Excelsior | 2 | Fernandez, De Graaf (P) | ||
| PSV | 3 | Lens, Hutchinson, Dzsudzsak (P) | ||||
| 06/03/2011 | Heerenveen | Heerenveen | 0 | |||
| Feyenoord | 1 | Castaignos | ||||
| 06/03/2011 | Groningen | Groningen | 1 | Tadic | ||
| Heracles | 4 | Everton (2), Armenteros (2) | ||||
| 06/03/2011 | Utrecht | Utrecht | 1 | De Kogel | ||
| Roda | 1 | Junker (P) | ||||
| 06/03/2011 | Amsterdam | Ajax | 4 | De Zeeuw, De Jong, Ebecilio, Anita | ||
| AZ | 0 | |||||
| 27º Fecha | ||||||
| 11/03/2011 | Utrecht | Utrecht | 1 | Demouge | ||
| Groningen | 0 | |||||
| 12/03/2011 | Almelo | Heracles | 4 | Fledderus, Quansah, Looms, Piet | ||
| Excelsior | 1 | Fernandez | ||||
| 12/03/2011 | Kerkrade | Roda | 1 | Hadouir | ||
| AZ | 2 | Sigthorsson, Marlens | ||||
| 12/03/2011 | Arnhem | Vitesse | 1 | Riverola | ||
| Heerenveen | 1 | Janmaat | ||||
| 13/03/2011 | Doetinchem | De Graafschap | 1 | Poepon | ||
| Ado den Haag | 0 | |||||
| 13/03/2011 | Rotterdam | Feyenoord | 2 | Castaignos, De Vrij | ||
| NAC | 1 | Jenner | ||||
| 13/03/2011 | Tillburg | Willem II | 1 | Janga | ||
| Ajax | 3 | De Jong, Vertonghen, Eriksen | ||||
| 13/03/2011 | Enschede | Twente | 2 | Brama, John | ||
| Venlo | 1 | De Regt | ||||
| 13/03/2011 | Nijmegen | NEC | 2 | George, Zomer | ||
| PSV | 2 | Dzudzsak, Lens | ||||
| 28º Fecha | ||||||
| 18/03/2011 | Alkmaar | AZ | 3 | Wernbloom, Poulsen, Martins | ||
| Vitesse | 1 | Van Ginkel | ||||
| 19/03/2011 | Breda | NAC | 0 | |||
| Groningen | 1 | Granqvist | ||||
| 19/03/2011 | Almelo | Heracles | 4 | Everton, Armenteros, Van der Linden, Douglas | ||
| Heerenveen | 2 | Vayrynen, Haglund | ||||
| 19/03/2011 | Venlo | Venlo | 0 | |||
| Willem II | 0 | |||||
| 19/03/2011 | Breda | NEC | 1 | George | ||
| De Graafschap | 0 | |||||
| 20/03/2011 | La Haya | Ado den Haag | 3 | Kubik, Immers, Derijck | ||
| Ajax | 2 | Vertonghem, Eriksen | ||||
| 20/03/2011 | Eindhoven | PSV | 1 | Bakkal | ||
| Utrecht | 0 | |||||
| 20/03/2011 | Rotterdam | Excelsior | 0 | |||
| Twente | 2 | Janssen (2, 1P) | ||||
| 20/03/2011 | Kerkrade | Roda | 3 | Hadouir, Junker, Biseswar (A) | ||
| Feyenoord | 0 | |||||
| 29º Fecha | ||||||
| 02/04/2011 | Enschede | Twente | 2 | Janssen (2, 1P) | ||
| PSV | 0 | |||||
| 02/04/2011 | Heerenveen | Heerenveen | 2 | Breuer, Dost | ||
| Excelsior | 3 | Roorda (2), Lagouireh | ||||
| 02/04/2011 | Doetinchem | De Graafschap | 1 | Rose | ||
| NAC | 3 | Leonardo, Lurling, Gorter (P) | ||||
| 02/04/2011 | Tillburg | Willem II | 4 | Lasnik (P), Biemans, Kah (A), Rigters | ||
| Roda | 5 | Kah, Skoubo, Vorner (2), De Fauw | ||||
| 02/04/2011 | Roterdam | Feyenoord | 0 | |||
| AZ | 1 | Benschop | ||||
| 03/04/2011 | Arnhem | Vitesse | 2 | Bony, Pedersen | ||
| NEC | 1 | Goossens | ||||
| 03/04/2011 | Utrecht | Utrecht | 2 | Duplan, Strootman | ||
| Ado den Haag | 3 | Vicento, Radosavljevic, Bulykin (P) | ||||
| 03/04/2011 | Groningen | Groningen | 3 | Tadic, Granqvist, Pedersen | ||
| Venlo | 2 | Vujcevic, Cullen | ||||
| 03/04/2011 | Amsterdam | Ajax | 3 | Olegue, De Jong, Ozbiliz | ||
| Heracles | 0 | |||||
| 30º Fecha | ||||||
| 08/04/2011 | Alkmaar | AZ | 1 | Elm (P) | ||
| NAC | 1 | Gorter (P) | ||||
| 09/04/2011 | Venlo | Venlo | 1 | Musa (P) | ||
| NEC | 4 | Davids, Goosens (2), Vleminckx | ||||
| 09/04/2011 | Rotterdam | Excelsior | 0 | |||
| De Graafschap | 0 | |||||
| 09/04/2011 | La Haya | Ado den Haag | 1 | Buijs | ||
| Vitesse | 0 | |||||
| 09/04/2011 | Tillburg | Willem II | 2 | Lasnik (P), Hallovic | ||
| Heracles | 6 | Everton (3), Overtoom (2, 1P), Quansah | ||||
| 10/04/2011 | Enschede | Twente | 1 | Janssen (P) | ||
| Roda | 1 | Bodor | ||||
| 10/04/2011 | Utrecht | Utrecht | 0 | |||
| Feyenoord | 4 | Fer, Leerdam, Biseswar, Wijnaldum | ||||
| 10/04/2011 | Amsterdam | Ajax | 2 | Sulejmani, Vertonghen | ||
| Groningen | 0 | |||||
| 10/04/2011 | Eindhoven | PSV | 2 | Lens, Toivonen | ||
| Heerenveen | 2 | Assaidi, Dost | ||||
| 31º Fecha | ||||||
| 15/04/2011 | Heerenveen | Heerenveen | 3 | Assaidi, Narsingh, Dost | ||
| Utrecht | 0 | |||||
| 16/04/2011 | Arnhem | Vitesse | 2 | Bony, Kashia | ||
| Groningen | 1 | Holla | ||||
| 16/04/2011 | Breda | NAC | 1 | Boussaboun | ||
| Excelsior | 2 | Bergkamp, Fernandez | ||||
| 16/04/2011 | Kerkrade | Roda | 5 | Wielaert, Junker (3), Kah | ||
| Venlo | 2 | Timisela, Uchebo | ||||
| 16/04/2011 | Alkmaar | AZ | 3 | Sigthorsson, Holman, Van der Velden | ||
| Ado den Haag | 1 | Derijck | ||||
| 17/04/2011 | Doetinchem | De Graafschap | 1 | Meijer | ||
| Twente | 1 | Landzaat | ||||
| 17/04/2011 | Nijmegen | NEC | 1 | Schone | ||
| Ajax | 2 | Sulejmani, Alderweireld | ||||
| 17/04/2011 | Almelo | Heracles | 0 | |||
| PSV | 2 | Dzsudzsak, Berg | ||||
| 17/04/2011 | Rotterdam | Feyenoord | 6 | Wijnaldum (2), Mysichi (2), Indi, Castaignos (P) | ||
| Willem II | 1 | Lasnik | ||||
| 32º Fecha | ||||||
| 22/04/2011 | La Haya | Ado den Haag | 1 | Bulykin | ||
| Twente | 2 | Ruiz, De Jong | ||||
| 23/04/2011 | Tillburg | Willem II | 2 | Lasnik, Levchenko | ||
| AZ | 1 | Sigthorsson | ||||
| 23/04/2011 | Almelo | Heracles | 2 | Everton, Overtoom | ||
| De Graafschap | 0 | |||||
| 23/04/2011 | Kerkrade | Roda | 5 | Hempte, Skoubo, Junker (2, 1P), Hadouir | ||
| NAC | 1 | Kolkka | ||||
| 23/04/2011 | Venlo | Venlo | 2 | Boymans (2) | ||
| Heerenveen | 2 | Vayrynen, Dost | ||||
| 24/04/2011 | Rotterdam | Feyenoord | 3 | Wijnaldum (2), Castaignos | ||
| PSV | 1 | Toivonen | ||||
| 24/04/2011 | Amsterdam | Ajax | 4 | Ebecilio (2), Eriksen, De Jong | ||
| Excelsior | 1 | Bovenberg | ||||
| 24/04/2011 | Utrecht | Utrecht | 4 | Yasuda (A), Martens, Strootman, Demouge | ||
| Vitesse | 2 | Kashia, Tighadouini | ||||
| 24/04/2011 | Groningen | Groningen | 3 | Enevoldsen, Tadic, Matavz | ||
| NEC | 1 | Zimling | ||||
| 33º Fecha | ||||||
| 01/05/2011 | Breda | NAC | 1 | Amoah | ||
| Heracles | 2 | Fledderus, Piet | ||||
| 01/05/2011 | Alkmaar | AZ | 5 | Sigthorsson (2), Holman, Pelle (2) | ||
| De Graafschap | 1 | Jungschager | ||||
| 01/05/2011 | Eindhoven | PSV | 2 | Berg, Marcelo | ||
| Vitesse | 1 | Lopez | ||||
| 01/05/2011 | Rotterdam | Excelsior | 3 | Roorda (2), Bergkamp | ||
| Utrecht | 1 | Demouge | ||||
| 01/05/2011 | Nijmegen | NEC | 5 | Vleminckx (4), Amieux | ||
| Roda | 0 | |||||
| 01/05/2011 | Venlo | Venlo | 3 | Musa (2), Uchebo | ||
| Feyenoord | 2 | Wijnaldum, Castaignos | ||||
| 01/05/2011 | Enschede | Twente | 4 | De Jong, Douglas, Jelic (A), Janssen (P) | ||
| Willem II | 0 | |||||
| 01/05/2011 | La Haya | Ado den Haag | 2 | Bulykin (2, 1P) | ||
| Groningen | 4 | Andersson (2), Petersen, Hiariej | ||||
| 01/05/2011 | Heerenveen | Heerenveen | 1 | Vayrynen | ||
| Ajax | 2 | Sulejmani, Eriksen | ||||
| 34º Fecha | ||||||
| 15/05/2011 | Amsterdam | Ajax | 3 | De Jong (2), Landzaat (A) | ||
| Twente | 1 | Janssen | ||||
| 15/05/2011 | Almelo | Heracles | 3 | Overtoom (2, 1P), Armenteros | ||
| Ado den Haag | 0 | |||||
| 15/05/2011 | Doetinchem | De Graafschap | 1 | Poepon | ||
| Venlo | 0 | |||||
| 15/05/2011 | Arnhem | Vitesse | 1 | Riverola | ||
| Excelsior | 4 | Fernandez, Roorda (2, 1P), Vincken | ||||
| 15/05/2011 | Kerkrade | Kerkrade | 0 | |||
| Heerenveen | 0 | |||||
| 15/05/2011 | Groningen | Groningen | 0 | |||
| PSV | 0 | |||||
| 15/05/2011 | Tillburg | Willem II | 0 | |||
| NAC | 1 | Jenner | ||||
| 15/05/2011 | Utrecht | Utrecht | 5 | Mertens (3), Van Wolfswinkel (2) | ||
| AZ | 1 | Martens | ||||
| 15/05/2011 | Rotterdam | Feyenoord | 1 | Castaignos | ||
| NEC | 1 | Schone | ||||